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|Section2= |Section3= }} Sialyl LewisX, also known as ''sialyl LeX'' and ''SLeX'', is a tetrasaccharide carbohydrate that is usually attached to O-glycans on the surface of cells. It is known to play a vital role in cell-to-cell recognition processes. It is also the means by which an egg attracts sperm - first to stick to it, then bond with it and eventually form a fetus. The discovery of the essential role that this tetrasaccharide plays in the fertilization process was reported in August 2011. ''Sialyl Lewis X'' is also one of the most important blood group antigens and is displayed on the terminus of glycolipids that are present on the cell surface. The ''Sialyl Lewis X'' determinant, E-selectin ligand carbohydrate structure, is constitutively expressed on granulocytes and monocytes and mediates inflammatory extravasation of these cells. Resting T and B lymphocytes lack its expression and are induced to strongly express ''sialyl Lewis X'' upon activation. The ''Sialyl Lewis X'' determinant is expressed preferentially on activated Th1 cells but not on Th2 cells. ==History== The term Lewis in its name comes from the name of a family of people who suffered from a red blood cell incompatibility. The studies done on these individuals’ red blood cells led to the discovery of sialyl lewis x. Sialyl lewis x is a very important red blood cell antigen present on the glycolipids on the plasma membrane of the cell. 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Sialyl-Lewis X」の詳細全文を読む スポンサード リンク
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